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基于DNA链置换的三级联组合分子逻辑电路设计

孙军伟 李智 王延峰

引用本文: 孙军伟, 李智, 王延峰. 基于DNA链置换的三级联组合分子逻辑电路设计[J]. 电子与信息学报, doi: 10.11999/JEIT190847 shu
Citation:  Junwei SUN, Zhi LI, Yanfeng WANG. Design of Three-cascade Combinatorial Molecular Logic Circuit Based on DNA Strand Displacement[J]. Journal of Electronics and Information Technology, doi: 10.11999/JEIT190847 shu

基于DNA链置换的三级联组合分子逻辑电路设计

    作者简介: 孙军伟: 男,1984年生,副教授,研究方向为生物信息处理与控制;
    李智: 男,1994年生,研究生,研究方向为DNA计算,DNA链置换;
    王延峰: 男,1973年生,教授,研究方向为生物信息处理与控制
    通讯作者: 王延峰,yanfengwang@yeah.net
  • 基金项目: 国家重点研发项目(2017YFE0103900),国家自然科学基金 (U1804262, 61632002),中原千人计划(204200510003),食管癌防治国家重点实验室开放基金(K2020-0010, K2020-0011)

摘要: DNA计算研究内容繁多复杂,DNA复杂逻辑电路的搭建属于DNA计算的一个重要研究分支,其中逻辑门的构建属于DNA复杂逻辑电路搭建的基础研究,设计出更为简单的逻辑门可以为研究者搭建复杂电路提供参考,节省基础研究的宝贵时间。针对上述问题,该文利用使能控制端思想,采用DNA链置换技术,设计了与或、与非或非和异或同或3种DNA组合逻辑门。结果上显示,设计的3种组合逻辑门可实现六种逻辑运算功能,并利用所构建的组合逻辑门成功构造了多级联组合分子逻辑电路,为DNA计算提供了更多的解决方案,促进了DNA计算机的发展。

English

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  • 图 1  与或组合逻辑门

    图 2  与或组合逻辑门仿真图

    图 3  与非或非组合逻辑门

    图 4  与非或非组合逻辑门仿真图

    图 5  异或同或组合逻辑门

    图 6  异或同或组合逻辑门仿真图

    图 7  四输入三级联组合逻辑电路

    图 8  四输入三级联组合逻辑电路

    表 1  四输入三级联组合逻辑电路真值表

    序号C1/C2C3/C4C5/C6Y序号C1/C2C3/C4C5/C6Y
    1ON/OFFON/OFFON/OFF(ABC)'⊕D6OFF/ONOFF/ONON/OFF((A+B)+C)'⊕D
    2ON/OFFON/OFFOFF/ON(ABC)'⊙D7OFF/ONON/OFFOFF/ON((A+B)C)'⊙D
    3ON/OFFOFF/ONON/OFF((AB)+C)'⊕D8OFF/ONON/OFFON/OFF((A+B)C)'⊕D
    4ON/OFFOFF/ONOFF/ON((AB)+C)'⊙D9OFF/OFFOFF/OFFOFF/OFFOFF
    5OFF/ONOFF/ONOFF/ON((A+B)+C)'⊙D10ON/ONON/ONON/ONON
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文章相关
  • 通讯作者:  王延峰, yanfengwang@yeah.net
  • 收稿日期:  2019-11-01
  • 录用日期:  2020-04-18
  • 网络出版日期:  2020-05-13
通讯作者: 陈斌, bchen63@163.com
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