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基于分子印迹聚合膜的胆固醇丝网印刷生物传感芯片

薛茜男 边超 任振兴 孙楫舟 卞贺明 韩泾鸿 夏善红

薛茜男, 边超, 任振兴, 孙楫舟, 卞贺明, 韩泾鸿, 夏善红. 基于分子印迹聚合膜的胆固醇丝网印刷生物传感芯片[J]. 电子与信息学报, 2010, 32(11): 2735-2739. doi: 10.3724/SP.J.1146.2009.01611
引用本文: 薛茜男, 边超, 任振兴, 孙楫舟, 卞贺明, 韩泾鸿, 夏善红. 基于分子印迹聚合膜的胆固醇丝网印刷生物传感芯片[J]. 电子与信息学报, 2010, 32(11): 2735-2739. doi: 10.3724/SP.J.1146.2009.01611
Xue Qian-Nan, Bian Chao, Ren Zhen-Xing, Sun Ji-Zhou, Bian He-Ming, Han Jing-Hong, Xia Shan-Hong. Screen Printing Bio-chip Sensor for Cholesterol Detection Based on Molecular Imprinting Self-assembled Film[J]. Journal of Electronics and Information Technology, 2010, 32(11): 2735-2739. doi: 10.3724/SP.J.1146.2009.01611
Citation: Xue Qian-Nan, Bian Chao, Ren Zhen-Xing, Sun Ji-Zhou, Bian He-Ming, Han Jing-Hong, Xia Shan-Hong. Screen Printing Bio-chip Sensor for Cholesterol Detection Based on Molecular Imprinting Self-assembled Film[J]. Journal of Electronics and Information Technology, 2010, 32(11): 2735-2739. doi: 10.3724/SP.J.1146.2009.01611

基于分子印迹聚合膜的胆固醇丝网印刷生物传感芯片

doi: 10.3724/SP.J.1146.2009.01611
基金项目: 

国家自然科学基金项目(60672019)资助课题

Screen Printing Bio-chip Sensor for Cholesterol Detection Based on Molecular Imprinting Self-assembled Film

  • 摘要: 该文基于自组装技术在丝网印刷金电极表面制备分子印迹膜,研制胆固醇电化学仿生生物传感芯片。利用扫描电镜(SEM)对平面裸金电极、厚膜裸金电极及其修饰电极进行了形貌的分析比较,采用循环伏安分析法对电极修饰过程的电化学特性进行表征,采用计时电流法对胆固醇生物传感芯片的浓度响应特性进行检测。结果表明, 基于丝网印刷工艺的厚膜电极不仅能满足自组装分子印迹仿生膜的修饰,而且电极表面具有明显的纳米放大效应。传感器对0~700 nM不同浓度胆固醇进行检测,线性范围50 nM~700 nM,灵敏度达到-4.94 A/[lg(nM)],线性相关系数为0.994。该胆固醇传感芯片具有较高的准确性,检测准确度达到了99.56%。
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    出版历程
    • 收稿日期:  2009-12-18
    • 修回日期:  2010-05-04
    • 刊出日期:  2010-11-19

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